Morning Briefing

Counter-counter-attack from Viking Therapeutics in the GLP-1 diabetes/weight loss drug war

Counter-counter-attack from Viking Therapeutics in the GLP-1 diabetes/weight loss drug war

First, it was Viking Therapeutics (VKTX) on the attack with trial results that shows its GLP-1 dibetes/weight loss drug out performing current leader of the pack drugs fro Novo Nordisk (NVO) and Eli Lilly (LLY). On the news Viking soared.

Then Novo Nordisk struct back with data of its own showing progress on an oral formulation of its rugs. (All existing GLP-1 drugs are delivered by injection.) That cratered Viking Shares. Now, March 26, Viking has released new Phase 1 trial data from a multiple ascending dose study of the oral version of VK2735, a dual agonist of the glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors.

Hey, Federal Reserve! What about the real world like, oh, wages?

Hey, Federal Reserve! What about the real world like, oh, wages?

You know the saying, When all you have is a hammer, every problem looks like a nail? How about this data world version, When you don’t track the data, you can’t see the problem? I was drawn to paraphrase the classic hammer/nail adage by the release of the Federal Reserve’s most recent economic projections, the Dot Plot, on Wednesday, March 20 when I thought about the economic data the Fed didn’t include in its projections.

Initial claims for unemployment drop for the week

Initial claims for unemployment drop for the week

Initial claims for state unemployment benefits dropped 2,000 to a seasonally adjusted 210,000 for the week ended March 16, the Labor Department reported today, March 21. Economists polled by Reuters had forecast 215,000 claims in the latest week. Continuing claims for unemployment increased 4,000 to 1.807 million during the week ending March 9, the report on Thursday showed. The Federal Reserve has been looking for signs that the labor market is weakening before raising interest rates. So far the evidence is inconclusive.

No surprise! on interest rates from the Federal Reserve today

No surprise! on interest rates from the Federal Reserve today

The Federal Reserve unanimously voted to leave the benchmark Fed Funds rate in a range of 5.25% to 5.5%, the highest since 2001, for a fifth straight meeting. They left their projections in the quarterly Dot Plot for the Fed Funds rate by the end of 2024 at 4.6%. That was the same projection as in the December Dot Plot. And nothing in either the post-meeting press statement or in Fed chair Jerome Powell’s press remarks changed the timing on when the Fed will make its first interest rate cut.

Credit card delinquency rates keep rising

About 8.5% of credit card balances and 7.7% of auto loans moved into delinquency in the fourth quarter of 2023, the Federal Reserve Bank of New York reported last week. “Credit card and auto loan transitions into delinquency are still rising above pre-pandemic levels,” said Wilbert van der Klaauw, economic research advisor at the New York Fed. “This signals increased financial stress, especially among younger and lower-income households.” Total household debt increased by $212 billion last quarter to $17.5 trillion

Saturday Night Quarterback says, For the week ahead expect…

Saturday Night Quarterback says, For the week ahead expect…

There’s room for disappointment in Wednesday’s Dot Plot projections from the Federal Reserve. Economists surveyed by Bloomberg were still expecting the Federal Reserve to cut interest rates three or more times in 2024 with the first cut coming in June. (To be more precise, the survey found that a majority expect three or more cuts in 2024 while more than a a third expect two or fewer cuts in 2024.) The survey was conducted from March 8 through March 13. Why do I highlight the dates?

Hotter than expected Wholesale Price Inflation adds to inflation/interest rate fears

Hotter than expected Wholesale Price Inflation adds to inflation/interest rate fears

It’s becoming a refrain. Today another inflation measure came in hotter than expected. Which is the problem. It’s har to ignore the possibility that inflation has stopped its steady decline and its recent months has started to move up again. Is there a problem here beyond a stickiness in prices that is preventing the Federal Reserve from reaching its inflation goals? And that might be endangering even a June timetable for an initial interest rate cut? Prices paid to U.S. producers rose in February by the most in six months.

No surprise! on interest rates from the Federal Reserve today

Why next week’s Dot Plot from the Fed is more important than ever after a hot inflation report

There’s not much question of what the Federal Reserve will do at its March 20 meeting. The odds–99% on the CME Fed Watch Tool–are that the Fed will do nothing and leave interest rates at the current 5.25%-5.50% benchmark. But that day the Fed will also release its most recent quarterly revision of its economic projections for the year ahead, the Dot Plot. And those projections will have, potential, market moving power. The central question: Will the Fed hold to its projection of 2 interest rate cuts in 2024 or will the bank, worried by recent evidence that inflation has been stubbornly high in recent months, point toward just one cut by the end of the year?

Core CPI inflation disappoints again for February

Core CPI inflation disappoints again for February

Core CPI inflation came in hotter than expected in February for a second straight month. The core Consumer Price Index, which excludes food and energy prices, increased 0.4% from January, the Bureau of Labor Statistics reported today. The year over year inflation rate rose to 3.8%. Economists had been projecting 3.7% annual rate. Core CPI over the past three months rose an annualized 4.2%, the highest annual rate since June. That adds to worries that the improvement in inflation has stalled in recent months.

Saturday Night Quarterback says (on a Sunday), For the week ahead don’t expect…

Saturday Night Quarterback says (on a Sunday), For the week ahead don’t expect…

A month after the stock market was rocked by a worse-than-expected inflation report, investors are fearing a reprise when the latest data arrives on Tuesday. Last Thursday stocks rallied when Fed Chair Jerome Powell said in his testimony before the Senate that the central bank is “not far” from being ready to cut interest rates. But this week Fed officials are in their regular blackout period ahead of their meeting on March 19 and 20. Absent Fed commentary on the inflation report, stocks may be volatile again.